Selected Publications

  1. W Hsu, N Gonzalez, A Chien, P Villablanca, P Pajukanta, F Vinuela, A Bui, "An Integrated, Ontology-Driven Approach to Constructing Observational Databases for Research", Journal of Biomedical Informatics, Jun; 55:132-42, 2015. [PDF]

  2. M Castro, N Peloc, A Chien, E Goldberg, CM. Putman, JR Cebral, “Aneurysm flow characteristics in realistic carotid artery aneurysm models induced by proximal virtual stenotic plaques: a computational hemodynamics study”. Proc. SPIE, 9417-81, Feb 2015. [PDF]

  3. A Chien, Q Yu, D Zosso, “Effectiveness of Flow Reduction is Related to Aneurysm Geometry based on Quantitative DSA Flow Analysis in 13 Flow Diverter-treated Aneurysms”, Journal of Vascular and Interventional Radiology (JVIR), Vol 26:S2, Feb 2015.

  4. V Lau, J Sayre, T Qi, A Chien, “Ruptured Aneurysms Tend to Have Prominent Blood Flow Changes at Aneurysm Neck”, Stroke, Vol. 46:77, 2015.

  5. A Chien, Q Yi, D Zosso, “Quantitative Analysis of the Blood Flow Reduction in Brain Aneurysms Treated by Flow Diverter Stents”, Stroke, Vol. 46:72, 2015.

  6. Q Yu, X Yang, T Cheng, F Liang, A Chien “Measurement of Intracranial Aneurysm Growth”, Stroke, Vol. 46:77, 2015.

  7. W Chang, M Huang, A Chien, “Emerging Techniques for Evaluation of the Hemodynamics of Intracranial Vascular Pathology”, The Neuroradiology Journal, 2015 Feb;28(1):19-27. [PDF]

  8. A Chien, G Duckwiler, F Vinuela, “Blood Flow Characteristics Changes Induced by Flow Diverting Stent in a Large Wide-neck Intracranial Aneurysm”, Journal of Vascular and Interventional Radiology (JVIR), Vol 26:1, Jan 2015.

  9. X Yang, T Cheng, A Chien, “Accurate Vessel Segmentation with Progressive Contrast Enhancement and Canny Refinement”, Proc. of ACCV, P2-07, 2014. [PDF]

  10. X Yang, KT Cheng, A Chien, “Geodesic Active Contours with Adaptive Configuration for Cerebral Vessel and Aneurysm Segmentation”, IEEE Pattern Recognition ICPR, 2014. [PDF]

  11. J Patti, F Vinuela, A Chien, ”Distinct trends of pulsatility found at the necks of ruptured and unruptured aneurysms”, J Neurointerv Surg. Mar;6(2):103-7, 2014. (Journal Cover) [PDF]

  12. B Dimapasoc, A Chien, “Parent Artery Curvature May Help Determine the Effectiveness of Flow Diverter Treatment”, Stroke, 45:76, 2014.

  13. S Patel, A Chien, “Natural History Simulation Models: Aneurysms Larger Than 9.5 mm and Aneurysms Growing Faster Than 0.36 mm/year Require Intense Clinical Care”, Stroke, 45:82, 2014.

  14. A Chien and F Vinuela, "IS FlowMap, A Novel Tool to Examine Blood Flow Changes Induced by Flow Diverter Stent Treatment —Initial Experiences with Pipeline Cases", J Neurointerv Surg. Nov;5 Suppl 3:iii43-7, 2013. [PDF]

  15. A Chien, F Liang, J Sayre, N Salamon, P Villablanca, and F Viñuela, "The Enlargement of Small, Asymptomatic, Unruptured Intracranial Aneurysms with no History of SAH - Different Factors May Relate to the Growth of Single and Multiple Aneurysms", J Neurosurg. Jul;119(1):190-7, 2013. [PDF]

  16. A Chien, J Sayre, F Vinuela, ”Quantitative comparison of the dynamic flow waveform changes in 12 ruptured and 29 unruptured ICA–ophthalmic artery aneurysms”, Neuroradiology. Feb;55(3):313-20, 2013. [PDF]

  17. A Chien, F Liang, N Salamon, P Villablanca, F Vinuela, "Follow-up of Large Intracranial Aneurysms Indicates Growth Frequency Varies According to Location and Size," Stroke, 44:28, 2013.

  18. A Chien, J Sayre, F Vinuela, "Hemodynamic Differences Found in Ruptured and Unruptured Aneurysms - Quantitative Comparison of 41 Cases from a Single Location," Stroke, 44:89, 2013.

  19. SV Patel, A Chien, "Identifying Aneurysm Growth Based on Imaging: A Size Increase of 0.8-0.9 mm is the Optimal Threshold to Classify Growth," Stroke, 44:78, 2013.

  20. A Chien, F Liang, J Sayre, N Salamon, P Villablanca, F Vinuela, "The Growth of Small, Asymptomatic, Unruptured Intracranial Aneurysms with no History of SAH -Different Risk Factors Associated with Single and Multiple Aneurysms," Stroke, 44:82, 2013.

  21. T Khoo , S Loo and A Chien, “Three-Dimensional Automatic Detection of Brain Aneurysm Growth", Annual UCLA School of Medicine Josiah Brown Poster Fair, 2011.

  22. C Lederman, L Vese and A Chien, “Automatic Morphological Comparison of Aneurysm Growth for Longitudinally Followed Unruptured Aneurysms”, Lecture Notes in Computer Science, Vol.6938(1), pp.396-403, 2011. [PDF]

  23. S Loo, F Viñuela and A Chien, “Computational hemodynamic analysis for brain aneurysms to investigate the mechanism of rupture for aneurysms in different size categories”, IEEE Proc Computational Biology and Bioinformatics, 2011. [PDF]

  24. A Chien, J Sayre, and F Viñuela, "Comparative Morphological Analysis of the Geometry of Ruptured and Unruptured Aneurysms", Neurosurgery, 2011. [PDF]

  25. A Chien, S Loo and F Vinuela, “Hemodynamic Force Dyssynchrony in Cerebral Aneurysms—A Quantitative Patient-Specific Aneurysm Flow Analysis at Single Location”, Proc. American Society of Neuroradiology 49th Annual Meeting, Washington, June, 2011. [PDF]

  26. A Chien, J Sayre, B Dong, J Ye and F Viñuela, “3D Quantitative Evaluation of Atherosclerotic Plaque based on Rotational Angiography”, American Journal of Neuroradiology, 2011. [PDF]

  27. W Ma, J-M Morel, S Osher and A Chien, “An L1-based variational model for Retinex theory and its application to medical images”, IEEE Proc Computer Vision Pattern Recognition, pp.153-160, 2011. [PDF]

  28. F Mut, R Löhner, A Chien, S Tateshima, F Viñuela, C Putman and J Cebral, "Computational Hemodynamics Framework for the Analysis of Cerebral Aneurysms", International Journal for Numerical Methods in Biomedical Engineering, 2010. [PDF]

  29. J Lee, A Chien and G Duckwiler, “Hemodynamic Analysis of Small Middle Cerebral and Basilar Artery Aneurysms”, Proc. WSMRF Annual Meeting, Monterey, CA, January 30, 2010. [PDF]

  30. A Chien, M Castro, S Tateshima, J Sayre, J Cebral and F Viñuela, “Quantitative Hemodynamic Analysis for Brian Aneurysms at Different Locations”, American Journal of Neuroradiology, Vol. 30, No.8, pp.1507-1512, 2009. [PDF]

  31. A Chien, S Tateshima, J Sayre, M Castro, J Cebral and F Viñuela, “Patient-specific Hemodynamic Analysis of Small ICA-Ophthalmic aneurysms”, Surgical Neurology. Vol. 72(5):444-50, 2009. [PDF]

  32. J Yi, J Schmidt, A Chien and C Montemagno, “Engineering Artificial Amoeba Propelled by Nanoparticle-triggered Actin Polymerization”, Nanotechnology, Vol 20(8), pp.85101, 2009.

  33. A Chien, S Tateshima, M Castro, J Sayre, J Cebral and F Viñuela, “Patient-specific Flow Analysis of Brain aneurysms at a Single Location: Comparison of Hemodynamic Characteristics in Small Aneurysms”, Medical & Biological Engineering & Computing, Vol. 46, pp. 1113-1120, 2008. [PDF]

  34. B Dong, A Chien, Y Mao, J Ye and S Osher, “ Level Set Based Surface Capturing in 3D Medical Images”, Lecture Notes in Computer Science, Vol. 5241, pp. 162- 169, 2008.

  35. A Buades, A Chien, J-M Morel and S Osher, “Topology Preserving Linear Filtering Applied to Medical Imaging”, SIAM Journal on Imaging Sciences, Vol. 1, pp. 26-50 2008.

  36. A Chien, R Shoucri, A Mal and C Montemagno, “Human Cardiac Wall Stress Analysis with Patient-specific Myocardial Material Properties”, WIT Transactions on Biomedicine and Health, Vol. 12, pp. 33-42, 2007.

  37. A Chien and C Montemagno, “Optimal Density and Locations of Laser Channels can be Predicted for Transmyocardial Laser Revascularization by a Three-dimensional Ventricular Simulation Model”, Lasers in Surgery and Medicine, Vol. 38, No.S18, pp. 53, 2006.

  38. A Chien, P Finn, N Boyle and C Montemagno, “Non-invasive Evaluation of 3-Dimensional Ventricular Wall Stress Changes throughout the Cardiac Cycle”, The International Journal of Cardiovascular Imaging, Vol. 21, No. 6, pp. 675-676, 2005.

  39. A Chien, H Dinh, P Finn and C Montemagno, “Human Dynamic in vivo Myocardial Wall Stress based on tagged Magnetic Resonance Imaging”, The International Journal of Cardiovascular Imaging, Vol. 21, No. 6, pp. 685, 2005.

  40. A Chien, N Boyle and C Montemagno, “Nonuniform Increases in Regional Wall Stress Encircle Infarcted Myocardium: A Derivation Using Left Ventricular Simulation”, Journal of Cardiac Failure, Vol. 10, No. 4, pp. S32, 2004.

  41. A Chien, P Finn and C Montemagno, “Non-invasive Derivation of 3D Systolic Nonlinear Wall Stress in a Biventricular Model from tagged MRI”, Lecture Notes in Computer Science, Vol. 3217, pp. 1067- 68, 2004.